'We basically got lucky that on my last attempt, he didn't Bestow himself and after 10 or so deaths, we got him.'

'I needed to force him into that fire, and he's a very difficult monster to manipulate to move,' said Macro. (The full explanation involves even more complexity than this it's in the video (opens in new tab) embedded above, starting at about 5:05.) If Lord De Seis stood in the fire, he'd take damage every frame, preventing him from regenerating. To deal damage faster than Lord De Seis could regenerate health, Macro needed an item that gave their character a 5% chance to cast Blaze, a spell which creates a burning patch on the ground. My background is in microbiology and science in general, so I've always been prone to asking the impossible questions. I couldn't survive his minions long enough to kill him, and if you die and go back to town, he will often cast a Bestow buff on himself that makes him regenerate faster than any amount of Nova procs from my gear could put out.' 'That quickly fell apart after eight hours trying to get a specific spawn pattern for the Seal Boss Lord De Seis in the Chaos Sanctuary. 'I thought this run would be tough, but with the addition of Synergies to the skill Nova in Diablo 2: Resurrected, I figured it would actually be a lot easier than it was in Lord of Destruction,' Macro told PC Gamer.

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